The goal of a new study published in Pediatrics assessed the association of anxiety and depression with increased asthma-related emergency department (ED) use for pediatric patients.In this study, patientswith asthma, aged 6-21 years, were selected from the Massachusetts All-Payer Claims Database from 2014-2015 using the International Classification of Diseases, Ninth and 10th Revision codes. The association between the presence of anxiety, depression or comorbid anxiety and depression and the rate of asthma-related ED visits per 100 child-years were examinedusing bivariate and multivariable analyses with negative binomial regression.The findings revealed that out of 65,342 patients with asthma, 24.7% had a diagnosis of anxiety, depression or both—11.2% anxiety only; 5.8% depression only; and 7.7% both. The overall rate of asthma-related ED use was 17.1 ED visits per 100 child-years. Controlling for age, sex, insurance type and other chronic illness, patients with anxiety had a rate of 18.9 ED visits per 100 child-years, patients with depression had a rate of 21.7 and patients with both, depression and anxiety, had a rate of 27.6. These rates were higher than those of patients who had no diagnosis of anxiety or depression.Hence, it was inferred that children with asthma and anxiety or depression alone or comorbid anxiety and depression, have higher rates of asthma-related ED use compared with those without either diagnosis.