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Children exposed to hyperemesis gravidarum (HG) in utero are more likely to be diagnosed with autism spectrum disorders (ASDs) than those whose mothers did not suffer from HG, according to a new retrospective cohort study.
The incidence of ASD among unexposed children was 1.71/1,000 person-years, while it was 2.87/1,000 person-years for HG-exposed children. HG diagnosis in the first (hazard ratio 1.58) and second (HR 1.36) trimesters were both associated with increased ASD risk. The findings are published online October 3 in the American Journal of Perinatology.