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For individuals who cannot or prefer not to take oral capsules, the same increase in vitamin D levels in the blood can be achieved with a sublingual spray, suggests a small randomized controlled trial.
Investigators examined the ability of a daily sublingual spray to raise serum vitamin D concentrations in 75 healthy volunteers. They showed that it not only markedly and significantly increased 25(OH)D levels in comparison with placebo, but the effect achieved with the spray matched that seen with a standard capsule. The findings were published online in the European Journal of Clinical Nutrition.