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Higher serum trans-fat levels have been associated with a significantly elevated risk of dementia, including Alzheimers disease (AD), results of a large, longitudinal study, published online October 23 in Neurology, show.
Participants with the highest concentrations of serum elaidic acid, a major trans-fatty acid formed in the partial hydrogenation of vegetable oils, had a 53% increased risk of dementia. This group also had a 43% higher likelihood for developing AD compared with those with the lowest levels.