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A large population-based study reports a definitive increase in risk for hip, pelvis, spine, and wrist fractures among adults with atopic dermatitis. The risk was even higher for patients with severe disease.
The researchers gathered study data from the electronic health and hospitalization records of approximately 527,000 British patients with eczema and more than 2.5 million control participants without eczema. Compared with matched healthy control persons, patients with atopic dermatitis had an overall increased risk for wrist fracture (7% increase; hazard ratio [HR], 1.07), hip fracture (10%; HR, 1.10), pelvis fracture (10%; HR, 1.10), and spine fracture (18%; HR, 1.18). The findings were published online November 19 in the Journal of Allergy and Clinical Immunology.