The purpose of a new study published in the Journal of the European Academy of Dermatology and Venereology was to determine associations of atopic eczema (AE) with depression, anxiety, quality of life (QoL) and social interactions in subjects from the population-based LIFE-Adult-Study. In this study, participants underwent interviews (medical history) and answered standardized questionnaires. Data from subjects with AE were compared with those from subjects with selected other chronic/disabling diseases (like cardiovascular, diabetes or cancer) and adjusted for selected sociodemographic parameters. The results revealed that of the 9,104 adult participants, 372 had a history of AE. Individuals with AE showed higher scores for depressive symptoms and anxiety, compared to the controls. The Odd’s ratio (OR) was 1.5 for depression, which was similar to the OR in patients with a history of cancer. However, OR for anxiety in AE was slightly higher than in patients of diabetes mellitus and stroke. Furthermore, excepting diabetes and/or stroke, a significant association was not found between AE and social isolation. Moreover, the QoL scores were lower in AE than in controls (mean 46.9 versus 48.0for physical and 50.6versus 52.5for mental components).