A new article published in Current Pediatric Reviews discussed that food allergy is a potentially life-threatening medical condition and its rising prevalence has led to a significant public health concern worldwide. Its current management consists of strict avoidance of the known allergenic food and treating any adverse reactions from unintended food ingestion. Here, the authors stated that allergen immunotherapy (AIT) entailsgradual administration of increasing amounts of the offending allergen in order to induce food desensitization—that is, an increase in threshold for reactivity while continuing on regular exposure to the allergen. AIT can be administered through oral, sublingual, epicutaneous and subcutaneous routes. Yet, reports on oral immunotherapy (OIT)have been more extensive. The desirable goal of AIT is to achieve ‘post desensitization effectiveness’ – the ability to introduce food without reaction even after a period of discontinuation of the offending food. This article also reported on other therapeutic approaches,that are simultaneously being studiedbesides immunotherapy, such as modified proteins, probiotics, Chinese herbal supplements, biologic therapies and DNA vaccines.