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#Diabetes and Endocrinology #Nephrology #Pharmacist #Transplantation
Compared with kidney transplantation alone, simultaneous pancreas-kidney (SPK) transplantation was associated with an almost twofold lower 10-year mortality among type 1 diabetics, in a retrospective study.
The study included all 2,796 patients with type 1 diabetes in the Netherlands who started renal replacement therapy or received a first kidney transplant between 1986 and 2016. As reported in Diabetes Care, of the 996 who received new kidneys, 42% received a deceased-donor kidney; 16%, a living-donor kidney; and 42%, an SPK transplant. Crude survival was highest in SPK recipients and lowest in recipients of a deceased-donor kidney. Median survival time was 7.3 years for deceased-donor kidney recipients; 10.5 years for living-donor kidney recipients; and 16.5 years for SPK recipients.