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COVID-19: Some of the unanswered or partially understood questions

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Dr KK Aggarwal    21 February 2020

  1. Why is the tripling rate in South Korea 72 Hours, which is much higher than in China?
  2. Is the concept of super-spreader scientific? Why is WHO saying we do not agree with this term.
  3. Is there a possibility of airborne transmission of COVID-19 in some situations?
  4. Why some individuals are more infectious than others?
  5. Can a coexisting infection or disease make the virus more transmissible or virulent?
  6. Can COVID-19 virus lead to chronic state of viremia like hepatitis B or C.
  7. Can recovered patients may still be infectious?
  8. Will the body end up becoming partly immune, like with flu, or almost completely immune, like chickenpox, after infection?
  9. Why the mortality is only in 59+ age and with comorbid conditions?
  10. Why only 20% of people are developing lower respiratory infections with breathlessness? And who are these patients?
  11. Can the virus cross the semen, like Zika and Ebola?
  12.  Can the virus remain in areas of the body that are immunologically privileged sites after acute infection? 

At these sites, viruses and pathogens, like Ebola, are protected from the survivor’s immune system, even after being cleared from elsewhere in the body. These include testes, interior of the eyes, placenta, and central nervous system, especially the cerebrospinal fluid. Whether the virus is present in these body parts and for how long varies from person-to-person.

  1. Why COVID-19 is sparing the children?
  2.  Both Severe Acute Respiratory Syndrome (SARS) and Middle East Respiratory Syndrome (MERS), had rapidly spread across the world from countries of their origin (China and Middle East, respectively), but largely remained out of India.
  3.  Why yellow fever never entered India when we have the mosquito and unvaccinated society. Are we different and more immune to certain viruses?

Dr KK Aggarwal,

President CMAA), HCFI and Past National President IMA

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