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Acute Kidney Injury with consumption of raw gall bladder of Indian carp fish.

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eMediNexus    04 December 2017

A new study published in Nephrology examined the clinical presentation and outcome of all patients who presented with acute kidney injury (AKI) following consumption of uncooked fish gallbladder of Indian carp fish – Labeo rohita, as folk medicine. This retrospective study reviewed all cases admitted at our institute between 1st January 1997 and 31st December 2016, following ingestion of fish gallbladder (Indian carp – Labeo rohita). The analysis included 32 patients with a male: female ratio of 3:1 and mean age 44.34 ± 13.33 years. It was found that all 32 patients presented with hepatic and renal failure. The mean duration of onset of symptoms following ingestion was 6.47±2.84 hours. At the time of admission, urine output was 187.9±141 ml/24 hours, serum creatinine 11.66±2.50 mg/dl, serum bilirubin 6.14±3.91 mg/dl, serum glutamic pyruvic transaminase (SGPT) 687±458 IU/L, and serum glutamic oxaloacetic transaminase (SGOT) 188±181 IU/L. Except for one patient, all others required hemodialysis. Eventually, 27 patients were discharged with recovering acute kidney injury while 5 patients died. Mean duration of hospital stay was 12.94±8.31 days. While, mean number of hemodialysis received by patients was 4.59±3.12. Moreover, interval between consumption and onset of symptoms, serum bilirubin and SGPT were found to be significantly different between those who survived and died. Therefore, it was concluded that AKI associated with the ingestion of raw fish gallbladder results in significant morbidity and mortality.

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