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A comparison of therapeutic management of adults with atopic dermatitis with psoriasis and chronic urticaria

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eMediNexus    21 April 2020

The management options in atopic dermatitis are based on consensus-based guidelines, also established for psoriasis and chronic urticaria. The treatment approach in atopic dermatitis, particularly in the moderate-to-severe forms of the disease, appears to be less aggressive than in psoriasis and chronic urticarial, with systemic agents used less frequently.

A recent study compared the therapeutic management of adults with atopic dermatitis to those with psoriasis and chronic urticaria in real life conditions.

Investigators conducted a transversal analysis in May 2017, using retrospective data from a monocentric database. Data were collected on epidemiology, severity, therapeutic educational intervention and systemic treatments from 401 patients with atopic dermatitis, and were compared with data from 230 patients with chronic urticaria and 535 patients with psoriasis.

About 73% of atopic dermatitis patients presented with a moderate-to-severe form of the disease compared to only 39% of chronic urticaria and 17% of psoriasis patients. Nearly 78% of the atopic dermatitis patients had completed a therapeutic educational program. On the contrary, the adherence was found to be lower in chronic urticaria (35%) and in psoriasis (3%) patients. A systemic treatment, including biologicals, was evident in 8% of atopic dermatitis patients, compared to 26% of chronic urticaria and 47% of psoriasis patients.

The findings revealed that atopic dermatitis treatment was predominantly based on topical regimens. Only a minority of moderate-to-severe atopic dermatitis patients who are eligible for systemic treatment receive such therapy.

Source: Pascal C, Maucort-Boulch D, Gilibert S, et al. Therapeutic management of adults with atopic dermatitis: comparison with psoriasis and chronic urticaria. J Eur Acad Dermatol Venereol. 2020 Mar 2.

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