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Circulating levels of progesterone may have a role in predicting future breast cancer incidence in older women, suggests new research published in JAMA Network Open.
Over a 12-year follow-up period, postmenopausal women had a modest 16% higher risk for breast cancer with each standard deviation increase in progesterone levels (hazard 1.16, 95% CI 1.00-1.35, P=0.048), reported researchers. The association between higher progesterone levels was shown to be even stronger for invasive breast cancers (HR 1.24, 95% CI 1.07-1.43, P=0.004).