A new study published in the Early Human Development evaluated the reproductive outcome of very low birth weight (VLBW, <1500g) infants who survive to adulthood (next-generation). This retrospective study included Infants born at a single tertiary center between 1982 and 1997, who survived till 18 years of age (first-generation). The results identified first-generation 67,183 births, including 618 VLBW; while 193 males and 184 female VLBW infants survived to adulthood. On the other hand, all first-generation patients from the VLBW group had half the reproductive rate when compared to the normal birth weight group. Moreover, male and female VLBW survivors had no significant risk for a VLBW neonate in the next-generation. Thus, it was inferred that VLBW infants who reach adulthood develop a significantly lower reproductive capacity.