A recent study published in the Turkish Journal of Medical Sciences aimed to determine the relationship between the peripheral blood neutrophil to lymphocyte ratio (NLR) and irritable bowel syndrome (IBS). This study enrolled 107 patients suffering from constipation-predominant IBS, diagnosed in accordance with the ROME III criteria and having complete blood count tests. While the control group comprised 106 healthy individuals with no relevant medical history. The findings revealed that the average peripheral blood NLR was 2.80 ± 2.52 in the IBS group; while the average range was 2.37 ± 1.65 in the control group. In comparison, the average NLR ratio in the patient group was statistically significant and higher than that of the control group. Hence, it was concluded that peripheral blood NLR, which is a reliable and precise indicator of inflammation in constipation-predominant IBS patients, detected with a simple complete blood count, was slightly elevated but statistically significant compared to the control group.¹

Reference

1. GÜÇLÜ M, AĞAN A. Relationship of peripheral blood neutrophil to lymphocyteratio and irritable bowel syndrome. Turkish Journal of Medical Sciences. 2017;47:1067-1071. doi:10.3906/sag-1509-44.