Multiple treatment modalities have been developed to treat atrophic acne scars with varying degrees of success. Post-inflammatory hyperpigmentation (PIH) after acne scar treatments remain a major concern in Asian patients. Fractional radiofrequency (FRF) has been used in many dermatological skin conditions including acne scars.

A new study published in the Journal of Cosmetic Dermatology aimed to determine the efficacy and safety of FRF nanoneedle system in the treatment of acne scars in Asians.

In this prospective, evaluator-blinded study, 23 subjects diagnosed with moderate-to-severe acne scarring were recruited. All subjects received 3 monthly treatments of the FRF nanoneedle system on both cheeks. Primary outcome was the clinical improvement of acne scars graded by two blinded dermatologists at baseline, 1-, 3- and 6-month follow-up. Objective scar volume analysis was done using ultraviolet A (UVA) light video camera. Subjects self-assessment, pain score and adverse events were also recorded.

The results showed clinical improvement of acne scars, as early as 1-month follow-up. Meanwhile, the acne scar volume decreased significantly on all follow-ups compared to the baseline. Nearly 48% of the subjects reported marked improvement in their scars. On the other hand, adverse events such as pain, erythema, burning sensation, edema, scab formation and PIH were mild and temporary.

Thus, it was concluded that FRF nanoneedle system is a safe and effective treatment for acne scars in Asians. It was further stated that despite the significant changes in the scar volume, caution should be practiced to avoid excessive coagulation resulting in PIH.

Source: Journal of Cosmetic Dermatology. 2020 May 16. doi: 10.1111/jocd.13484.