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Potential of cumulative ECG risk score in improving identification of individuals at high risk of sudden cardiac death

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eMediNexus    15 December 2017

In a study printed in the European Heart Journal, the investigators assessed whether a cumulative electrocardiogram (ECG) risk score would improve identification of individuals at high risk of sudden cardiac death (SCD). The findings revealed that this novel cumulative ECG risk score displays an independent association with sudden cardiac death and appears to be particularly effective for left ventricular ejection fraction (LVEF) >35% where risk stratification is currently not available. After adjusting for clinical factors and LVEF, increasing ECG risk score was associated with progressively greater odds of SCD. It was reported that individuals with ≥ 4 ECG abnormalities had an odds ratio (OR) of 21.2 for SCD. In the LVEF > 35% subgroup, the OR was 26.1. In the Atherosclerosis Risk in Communities (ARIC) cohort validation, risk of SCD related to ≥ 4 ECG abnormalities remained significant after multivariable adjustment.

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