Microneedling in combination with the use of growth factors can help with a range of indications, including skin rejuvenation. This procedure offers regeneration and is becoming popular as part of the regenerative, minimally invasive era.

The purpose of a new study published in the Journal of Cosmetic Dermatology was to examine the efficacy of a course of two sessions of growth factor-induced therapy using propriety preparation of AQ recovery serum.

This study recruited 30 women with various ethnic backgrounds – Chinese, Caucasian and Latino, of an average age of 38 years, who presented with mild-to-moderate visual facial ageing signs. Here, two sessions at two-week intervals were completed using a derma stamp – transdermal drug delivery method and 2ml of growth factor serum – AQ Skin Solution recovery serum—containing a mix of transforming growth factor beta (TGF-β), granulocyte monocyte-colony stimulating factor, and platelets-derived growth factor with patented technology for extraction and composition—at each session. The procedures were carried out for anti-ageing and skin rejuvenation. Clinical assessment, VISIA photography, independent assessment of before and after photos baseline and six weeks by two clinicians and two laypersons were carried out. The participants used FACE-Q questionnaire (outcome satisfaction) and scored changes in terms of their skin texture, radiance, pore size, wrinkles, pigmentation, tightness and overall skin appearance.

Physicians global assessment revealed growth factor induced therapy resulted in skin rejuvenation in all races with 95% confidence, and this increased to 98% confidence for Latinos and Caucasians within the six weeks. Participants subjective rating revealed improvement of overall skin appearance with 95% confidence. Most noted improvements were in brightness, skin texture and tightness.

Hence, the results demonstrated improvements in overall skin appearance, brightness, skin texture and tightness. It was stated that growth factor-induced therapy using propriety preparation of AQ recovery serum treatment is non-invasive and safe, with no or minimal downtime and high participant satisfaction.

Source: Journal of Cosmetic Dermatology. 2020 Oct 6. doi: 10.1111/jocd.13750.