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Children at risk of future obesity should be evaluated for body mass index (BMI) rebound. BMI rebound age refers to the age at which BMI reaches its lowest point before rising through later childhood, adolescence and adulthood.
An earlier BMI rebound age is associated with adverse risk factors for heart disease as noted at age 7, which include higher BMI, higher systolic and diastolic blood pressures, higher levels of serum insulin and leptin, higher left ventricular mass and left atrial size.
Early BMI rebound age for children is lower than 4.4 years for boys and 4.2 years for girls. Normal values are 4.4 to 6.6 years for boys and 4.2 to 5.7 years for girls.
All children who start gaining weight between 3 and 4 years should be classified as high risk for future diabetes and heart disease.