Systemic isotretinoin is frequently used in patients with severe and persistent acne. In a case report, a stable remission of inflammation, aesthetic correction of scars, and a positive impact on the psychological status and social adaptation resulted from 2-years of treatment of the patient with systemic isotretinoin and laser treatment plan. At the first stage, a course of vascular laser Nd: YAP/KTP 1079/540 nm in areas with a tendency to hypertrophic growth on the face and neck; at the second stage, the use of the Er:YAG laser 2940 nm with SMA technology for all type’sscars.

Following four sessions using the vascular laser with an interval of 2-3 weeks led to a clinical efficacy which was reflected in the elimination of itching, the reduction of the scar density, decrease of vascularization. Following two years of treatment of the patient with severe widespread acne conglobata with the resistant course, the DLQI decreased from 24 (extreme effect on the quality of life) to 6 (moderate effect).

Resource: Kalashnikova NG, Igorevna AV, Mohammad J. Laser treatment of acne conglobata with concomitant oral isotretinoin use. Dermatologic therapy. 2020; DOI: 10.1111/dth.14553Accessed fromhttps://pubmed.ncbi.nlm.nih.gov/33205848/