Analysis of data from over 250,000 women suggests that the use of oral contraceptives is tied to a diminished risk of ovarian and endometrial cancer about 30 years following discontinuation.

The use of oral contraceptives was also found to be linked to a short-term increased risk of breast cancer following discontinuation. However, the lifetime risk of breast cancer was not significantly different.

Investigators assessed data from 256,661 women from the U.K. Biobank, born from 1939 to 1970. Overall, 17,739 cases of breast cancer (6.9%), 1,966 cases of ovarian cancer (0.76%), and 2,462 cases of endometrial cancer (0.96%) were noted. The odds of ovarian cancer (OR, 0.72) and endometrial cancer (OR, 0.68) were lower among ever users, in comparison with never users… (Medscape)