Neonates and infants are vulnerable to skin barrier disruption as their skin is still developing anatomically and functionally. The process of skin acidification plays a major role in barrier maturation and the activation of enzymes involved in the extracellular processing of stratum corneum lipids.

A new study published in the Journal of Drugs in Dermatology explored challenges, and current treatment approaches in neonatal and infant normal and sensitive skin, and the role of ceramides containing moisturizers.

In this current consensus paper, an expert panel of pediatric dermatologists and dermatologists discussed information from systematic literature searches, coupled with expert opinion and experience of the panel, to adopt eight statements.

The consensus statements informed – during the first years after birth, the neonatal and infant skin is more permeable to topical agents, and hence, topical skincare regimens must be carefully selected. Mildly acidic or pH-neutral cleansers have benefits for neonates and infants. Furthermore, skincare products for neonates and infants should be safe, effective and fragrance-free, and devoid of sensitizing agent. In addition, they should be pleasant to use, containing ingredients that benefit the lipid and water content of the stratum corneum, for example, products containing ceramides.

In inference, it was stated that considering the maturation process of neonatal and infant skin, the application of moisturizers and cleansers containing barrier lipids may help maintain the protective skin barrier and soothe with long-term moisturizing benefits.

Source: Journal of Drugs in Dermatology. 2020 Aug 1;19(8):769-776. doi: 10.36849/JDD.2020.5252.