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Taurine Reverses Oxidative Damages and Restores the Muscle Function in Overuse of Exercised Muscle

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eMediNexus    01 May 2021

A recent article published in Frontiers in Physiology stated that exercise-induced oxidative stress is linked with the expression level of endogenous antioxidants. However, these antioxidants cannot overcome all oxidative stress-related damages in the cells caused by physiological stress. 

The authors informed that taurine – a sulfur-containing amino acid, is used for various physiological functions, but, its synthesis and accumulation under the oxidative environment may be compromised. Recent evidence suggests that taurine level is increased during exercise performance with a decrease in oxidative damage in overused muscles. While short-term supplementation with taurine increases physiological performance during severe work intensities, suggesting the role of taurine in improving muscle performance during exercise. 

On the other hand, the precursor of taurine – cysteine, is used in the synthesis of other compounds like GSH and Coenzyme A, which are important for regulating the redox system and energy homeostasis. This article summarized by stating that it is important to understand whether taurine synthesis within the cells can supress the activity of other compounds that are beneficial in preventing oxidative damage during intense exercise. Furthermore, it is important to understand whether taurine supplementation can prevent the conditions observed in the physiological stress of muscles. 

Source: Frontiers in Physiology.2020 Oct; 11: 582449. doi: 10.3389/fphys.2020.582449

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