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Dr KK Aggarwal 10 May 2021
New research published in The Lancet Respiratory Medicine has found that seropositive healthy young adults are still at risk of reinfection.
A prospective cohort study was conducted as part of the COVID-19 Health Action Response for Marines study (CHARM) to examine the risk of reinfection in healthy young adults who were seropositive for a previous SARS-CoV-2 infection. The study included male recruits, aged 18–20 years, from the US Marine Corps. They were first put under a two-week unsupervised home quarantine followed by a two-week supervised quarantine when they returned to the marine quarantine facility.
These observations indicate that although antibodies produced as a result of the infection are generally protective, they do no ensure effective immunity against subsequent infection. A risk still exists albeit a small one. In previously infected young adults, vaccination further enhances the natural immune response to prevent reinfection and reduce transmission. Hence, an aggressive vaccination strategy needs to be pursued to slow down the pandemic.
(Source: Lancet Respiratory Medicine, Published April 15, 2021)
Dr KK Aggarwal
President CMAAO, HCFI and Past National President IMA
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