EXPLORE!

Controversies in Lipid Management

  1005 Views

Dr Devendra Prasad Singh, Bhagalpur    06 January 2018

  1. In contrast, Mediterranean diet consistently lowers CV events without lowering cholesterol level.
  2. Framingham studies have shown association of high cholesterol and triglycerides with CVDs. It has been argued that association does not mean causation and many trials show that statins are no good; hence, the controversies.
  3. Statins are not without side effects; 30% patients taking statins have muscle aches and rarely rhabdomyolysis. Long-term statin therapy causing T2DM and dementia, further questions the utility of statin therapy.
  4. Recent controversy is regarding dosing approach. Fixed-dose-treatment vs. titrating-to-target level neither of these approaches is inferior.
  5. CAD is an extremely complex malady. Until the controversies of cholesterol hypothesis vs. alternate mechanism of pathogenesis of atherosclerosis are settled, statin therapy will stay along with healthy lifestyle, Mediterranean diet and aspirin in the prevention of CVDs.

To comment on this article,
create a free account.

Sign Up to instantly get access to 10000+ Articles & 1000+ Cases

Already registered?

Login Now

Most Popular Articles

News and Updates

eMediNexus provides latest updates on medical news, medical case studies from India. In-depth medical case studies and research designed for doctors and healthcare professionals.