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Dr Surya Kant Professor and Head Department of Respiratory Medicine, KGMU ,UP, Lucknow; National Vice Chairman IMA-AMS. 06 June 2021
A new study has shown that the risk of being infected with the coronavirus is reduced considerably for up to 10 months following the first infection.
The prospective VIVALDI study published in The Lancet Health Longevity evaluated over 2000 care staff (aged <65 years) and residents (>65 years age) at 100 long-term care facilities (LTCFs) in England between 1st October 2020, and 1st February 2021. The aim of the study was to see if there was an association between the baseline SARS-CoV-2 antibody status and subsequent infection in them. Blood samples were collected between June and November, 2020, at baseline, and 2 and 4 months thereafter and tested for IgG antibodies to SARS-CoV-2 nucleocapsid and spike proteins.
Analysis of up to 10 months of data of follow-up from primary infection (assuming earliest infections occurred in March 2020) revealed the following key findings.
These observations are from LTCFs owned by one particular healthcare group. Data from other LTCFs are also now being analysed.
Based on their findings, the study authors concluded that although they were vulnerable to reinfection, the risk was considerably reduced among staff and residents who had IgG antibodies to nucleocapsid protein suggesting that the antibodies provides a high degree of protection against a second infection for up to 10 months. Also, only few reinfections were detected and those that occurred were not severe.
(Source: Krutikov M, et al. Incidence of SARS-CoV-2 infection according to baseline antibody status in staff and residents of 100 long-term care facilities (VIVALDI): a prospective cohort study. The Lancet Health Longevity. Published June, 2021)
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