The researchers conducted a study to evaluate the association between advanced echocardiographic parameters and ischemic stroke, independent of CHA₂DS₂-VASc score. The results published in the European Heart Journal showed that the assessment of left atrial reservoir strain and P-wave to A′ duration on tissue Doppler imaging (PA-TDI) on echocardiography after initial CHA₂DS₂-VASc scoring offers additional risk stratification for stroke. It was shown that left atrial reservoir strain and PA-TDI were independently linked with the risk of stroke in a model including CHA₂DS₂-VASc score, age, and anti-coagulant use. They may help in formulating decisions regarding the use of anti-coagulation for patients upon first diagnosis of atrial fibrillation.