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Chronic Kidney Disease Linked to SARS-CoV-2 Infection

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eMediNexus    28 August 2021

The recent COVID 19 pandemic has increased concerns about the diagnosis of chronically ill patients and their follow-up. It has been observed that patients suffering from chronic illnesses, concomitantly infected by SARS-CoV-2, are associated with a worse prognosis and poor outcomes. Literature has shown renal tropism and acute kidney injury in patients after infection with SARS-CoV-2 with increased mortality rates. Patients with pre-existing chronic kidney disease and simultaneous SARS-CoV-2 infection should be regularly monitored. 

In a case of a 69-year old patient with splenic marginal zone lymphoma, suffering from long-term chronic kidney disease after SARS-CoV-2 infection. This case focused on the significance of monitoring kidney function in immunosuppressed patients and those who have cancer after SARS-CoV-2 infection via histological screening. 

Considering the occurrence of renal damage associated with SARS-CoV-2 infections, the increased incidence of acute kidney injury and acute tubular necrosis with SARS-CoV02 replication in proximal convoluted tubules in severe and fatal forms of SARS-CoV-2 infections. Available data points towards CKD as an important risk factor of severe and prolonged SARS-CoV-2 infection. 

Reference: Tarris G, Rougemont Ade, Estienney M-A, Journet J, et al. Chronic kidney disease linked to SARS-CoV-2 infection: a case report. BMC Nephrology. 2021; 22: 278. 

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