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New Tool May Accurately Predict Risk of Aneurysm Rupture after Growth

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eMediNexus    08 September 2021

A new prediction model may be able to accurately predict aneurysm rupture within a year after growth is identified on imaging, suggests research published online in JAMA Neurology.   

Investigators noted that the "triple-S" prediction model evaluates aneurysm size, site, and shape and can serve as a "starting point" to guide treatment and management. Investigators evaluated 312 adult patients with 329 aneurysms that had shown growth of at least 1 mm or more in one direction at follow-up imaging. About 7.6% of the aneurysms ruptured over 864 aneurysm-years of follow-up. The absolute risk for rupture following growth was estimated as 2.9%, 4.3% and 6% at 6 months, 1 year, and 2 years, respectively. Multivariable analyses suggested that the predictors of rupture included size >7 mm (hazard ratio [HR], 3.1), irregular shape (HR, 2.9), and being located in the middle cerebral artery (HR, 3.6) and the anterior cerebral artery, posterior communicating artery, or posterior circulation (HR, 2.8)… (Medscape)

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