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eMediNexus 24 September 2021
A cohort study from California described the importance of extended observation of atopic eczema beyond childhood to reveal clear subtypes based on patterns of disease activity.
Nearly 20% of children in industrialized settings are affected with atopic eczema with different disease patterns. However, recent researches have demonstrated its prevalence to be about 7%-10% in the adult population as well.
Abuabara K. et al reported a lack of prospective studies that examine the course of atopic eczema beyond adolescence and thus they examined the association of early-life risk factors and characteristics with subtypes of atopic eczema, determined their association with atopic disease and other general midlife health.
Study Design-
The observations of the study were as follows-
o Most people reporting no atopic eczema or reporting it rarely,
o Decreasing probability,
o High probability,
o Increasing probability of reporting atopic eczema with age.
Thus the researchers favored the extended observation of atopic disease beyond childhood, as clear subtypes of atopic eczema based on patterns of disease activity were found in the study.
Additionally, the Early- life factors linked with childhood atopic eczema, provided no differentiation between subtypes, indicating disease trajectory to be modifiable and may be influenced by environmental factors throughout life.
Source: Butera A. Investigators Reveal Subtypes in Atopic Dermatitis Disease Activity, Dermatology Times, 2021.
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