According to a small randomized controlled trial, treatment with omega-3 fatty acids among frail elderly with COVID-19 may have a role in improving lipid responses and reducing the levels of proinflammatory lipid mediators.

The study, presented at the European Geriatric Medicine Society (EuGMS) annual congress, included 22 patients with several comorbidities. Patients were administered either an intravenous infusion of an omega-3 polyunsaturated fatty acid (PUFA) emulsion of 10 g fish oil/100 mL or saline placebo. Those who were given the intravenous infusion were found to have a significant reduction in the neutrophil-to-lymphocyte ratio (NLR) from baseline to the end of treatment, which suggested considerable reductions in systemic inflammation. On the other hand, patients administered a saline placebo had no significant improvements in NLR. However, omega-3 fatty acids were not significantly associated with a decrease in C-reactive protein (CRP) or interleukin-6… (Medscape)