A new study published in Photobiomodulation, Photomedicine and Laser Surgery assessed the safety and efficacy of a 675-nm laser source on melasma. 

The study tested the efficiency and tolerance of up to three sessions of the 675-nm laser through a 5-point visual analogue pain scale (VAS) in patients with Fitzpatrick phototypes IV to V. 

The results depicted a mean 3.1 ± 0.7 improvement, according to photographic evaluation by VAS. Patients treated who received only one session showed mean clearance of 3.3 ± 0.76; patients who received two sessions exhibited mean clearance of 3.0 ± 0.71; and those treated with three sessionshad a mean clearance of 3.0 ± 1. While the pain score mean was 1.2 ± 0.4.

From the findings, it was inferred that 675-nm laser system is safe and effective for the treatment of facial melasma in patients with Fitzpatrick phototypes IV to V.

Source: Photobiomodulation, Photomedicine and Laser Surgery. 2021 Oct;39(10):634-636.doi: 10.1089/photob.2021.0076.