A randomized trial of around 26,000 adults conducted to evaluate the effects of vitamin D and omega-3 fatty acid supplementation on incident cancer and cardiovascular disease has shown that 5 years of vitamin D supplementation was tied to a 22% reduction in the risk for confirmed autoimmune diseases, and omega-3 fatty acid supplementation for 5 years was linked with an 18% decline in confirmed and probable incident autoimmune diseases.

These are nontoxic and well-tolerated supplements and there are no other well-established effective therapies for reducing the incidence of autoimmune diseases, said Karen H. Costenbader, of Brigham & Women′s Hospital in Boston, Massachusetts. Therefore, the significance of these results is very high, she said. The findings were presented at the virtual annual meeting of the American College of Rheumatology… (Medscape)