Lowering blood pressure can prevent the onset of diabetes; however, the effects may vary according to the antihypertensive drug class, suggests a meta-analysis.

Angiotensin-converting enzyme (ACE) inhibitors and angiotensin II receptor blockers (ARB) have the strongest association with prevention of diabetes onset, while beta-blockers and thiazide diuretics appear to be tied to an increased risk of new-onset diabetes, noted the analysis, published in The Lancet. It suggests that besides the well-known beneficial effects of reducing cardiovascular events, BP lowering can also help prevent diabetes, noted Milad Nazarzadeh and colleagues with the Blood Pressure Lowering Treatment Trialists′ Collaboration. The varying effects of the drug classes help decision-making for antihypertensive drug choice based on an individuals risk profile, noted investigators… (Medscape)