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Bromhexine hydrochloride: Potential role in pediatric COVID-19

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eMediNexus    07 March 2022

References

  1. Fu Q, Zheng X, Zhou Y, et al. Re-recognizing bromhexine hydrochloride: pharmaceutical properties and its possible role in treating pediatric COVID-19. Eur J Clin Pharmacol. 2020;1–3.
  2. Li T, Sun L, Zhang W, et al. Bromhexine Hydrochloride Tablets for the Treatment of Moderate COVID-19: An Open-Label Randomized Controlled Pilot Study. Clin Transl Sci. 2020 Nov;13(6):1096-1102.

What is the message here?

Considering the potential of bromhexine to inhibit TMPRSS2 and its beneficial effects in adult COVID-19 patients, it appears that it could have potential benefits in children as well and should be evaluated in the pediatric population.

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