A study published in the Neurourology and Urodynamics reviewed studies on prevalence, clinical symptoms, and associated risk factors, as well as formulated recommendations for the assessment and treatment of nocturnal enuresis (NE) and daytime urinary incontinence (DUI). For this review, a systematic Scopus search was conducted and relevant publications were selected. It was found that 1-2% of older adolescents are affected by NE and 1% by DUI. Moreover, NE and DUI are associated with multiple risk factors, such as fecal incontinence and constipation, obesity, chronic illness, and psychological impairment. Furthermore, chronic treatment-resistant, relapsing and new-onset cases are not uncommon. Meanwhile, adolescent NE and DUI can be treated by a multidisciplinary team based on pediatric principles. It was also stated that additional treatment components have been developed for adolescents. In summary, it was stated that since adolescents are evaluated by both pediatric and adult health care personnel, alignment and harmonization of diagnostic and therapeutic principles are essential in order to address nocturnal enuresis (NE) and daytime urinary incontinence (DUI) in adolescents.