• In a Japanese study, it was suggested that vaccination-induced antibody acquisition rates against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) were extremely low in patients who underwent post-kidney transplantation.
• The SARS-CoV-2 mRNA vaccines have shown high efficacy in developing antibodies in healthy individuals and are thus known to be effective against preventive infections.
• It has been reported that immunocompromised patients, such as those with underlying diseases are at high risk for developing severe diseases and should follow all protective measures to prevent infections.
• Thus, patients post-kidney transplant may remain at risk of infection with only two doses of vaccination.
• It is recommended that even though two doses of vaccination, these patients should be closely monitored for infection control. 

Reference

Fujieda K, Tanaka A, Kikuchi R, et al. Antibody response to double SARS-CoV-2 mRNA vaccination in Japanese kidney transplant recipients. Sci Rep. 2022;12:6850.