In a study published in the American Journal of Cardiology, 17,898 patients were retrospectively studied to compare long-term outcomes in those who underwent percutaneous coronary intervention (PCI) with varying severity of diabetes mellitus with and without chronic kidney disease (CKD). The results showed that adjusted hazard ratios for death or myocardial infarction associated with non-insulin type 2 diabetes mellitus and insulin requiring type 2 diabetes mellitus were 1.65 and 3.78, respectively in the absence of CKD. Analogous risks in the presence of CKD were 3.34 and 6.26. It was thus concluded that the need for insulin in patients with diabetes mellitus identifies a group at high risk of death or myocardial infarction at 1 year, regardless of the renal status.