In the review study published in the journal Ageing Research Reviews, researchers revealed that COVID-19 infection can predispose individuals to develop irreversible neurological conditions. COVID-19 is known to invade and infect the brain, among other major organs. Several brain imaging studies on COVID victims and survivors have shown the formation of microbleed lesions in the deeper brain regions related to cognitive and memory functions.

The study by Houston Methodist researchers confirmed that COVID infection can increase the likelihood of strokes and the development of persistent brain lesions that can lead to brain bleeding. According to the study, microbleeds are emerging neuropathological features identified in people suffering from chronic stress, depressive disorders, diabetes, and age-associated comorbidities. The investigators of the study found that COVID-induced micro-hemorrhagic lesions can aggregate DNA damage in affected brain cells. This damage can result in neuronal senescence and activation of the apoptosis mechanism.

The study associated this pathological phenomenon with the hallmark features of other neurodegenerative conditions like Alzheimer’s and Parkinson’s disease. The study also suggested various strategies to improve long-term neuropsychiatric and neurodegenerative outcomes. The study also outlined the importance of the therapeutic regimen of nanozymes in combination with various FDA-approved drugs to fight against neuronal diseases. 

(Source: https://health.economictimes.indiatimes.com/news/industry/covid-infection-may-accelerate-brain-ageing/93270761 )