The study published in BMJ Open Diabetes Research and Care revealed that leucocyte telomere length (LTL) is linked to obesity in pre-diabetic and type 2 diabetic women. The study addressed the relationship between pre-diabetes, truncal obesity, and LTL. The study observed that the shortening of LTL increased the rate of aging among women and increased the risk of premature death. 

LTL is the most commonly used measure to study age-dependent shortening and the risk of disease development in the human population. The study was conducted by researchers from Fortis C-Doc Hospital for Diabetes and Allied Sciences and partners. Dr. Anoop Misra, Executive Chairman and Director, Fortis C-Doc, stated that telomere shortening in Asian Indian women is a major contributor to pre-diabetes and may result in decreased longevity. 

The study found that LTL in women was associated with abnormal fasting glycemia (pre-diabetes). They found that the average LTL was significantly shorter in obese women with pre-diabetes. The R-squared statistic for the multivariable linear model was inversely correlated with Body Mass Index, waist and hip circumference, waist-hip and waist-to-height ratio, truncal skin folds, fat mass, and body fat percentage. The multivariable linear model was used after adjusting for age, family income, education, and hypertension. The study concluded that besides age, obesity and fat distribution in the truncal parts of the body are major contributors to telomere shortening in women with abnormal fasting glucose.

(Source: https://www.hindustantimes.com/lifestyle/health/leucocyte-telomere-length-is-linked-to-obesity-in-pre-diabetic-and-type-2-diabetic-women-101659680515139.html )