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Management of Dyslipidemia in Chronic Kidney Disease

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Dr Sonika Puri, New Brunswick, NJ    27 August 2022

  • Chronic kidney disease (CKD) is a vital risk factor for coronary artery disease (CAD).
  • Advance CKD is associated with high CV mortality related to CAD and nonatherosclerotic cardiac disease.
  • LAI recommends using statins in patients with CKD stage 3 above the age of 40 years.
  • LAI also recommends cautious initiation of statins in statin-naïve patients on dialysis.
  • Individual’s predicted longevity has to be kept in mind while initiating statin therapy in end-stage renal disease (ESRD).
  • Dose reduction with a decline in glomerular filtration rate.
  • Drug interactions with fibrates and anti-rejection medications.
  • Frequent monitoring for side effects is required.
  • Role of PCSK9 inhibitors: promising, but more data is needed.

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