A recent report describes a case of a man in his 50s who presented with pruritus, a burning sensation and associated blistering over his neck, chest and legs for 2 days. He described a history of coronary artery bypass grafting (CABG) for double-vessel blockage 2 days before the onset of these symptoms. 

Physical examination showed dusky-red to dark brown macules extending linearly over lateral aspects of the neck, upper back, shoulders and axilla, outlining the ECG electrodes initially placed during the surgery. He also showed scattered vesicles and bullae, especially around the ankle areas. The linear configuration of the lesions, including bizarre dribbling marks on convexities, suggested a liquid to be the cause of the presentation. 

The patient denied any history of exposure to iodine-containing topical preparations. His lesions entirely resolved in a week with slight post-inflammatory hyperpigmentation. 

After the resolution, the patient was offered a repeat open application test (ROAT) to confirm the diagnosis, but he denied remembering the severity of the reaction.

Source: Kaur M, Karadia P, Singh S. Povidone-iodine-induced disseminated irritant contact dermatitis. BMJ Case Rep. 2022;15(11):e251926.