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Safety of bowel cleansing using polyethylene glycol with ascorbic acid before pediatric colonoscopy.

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eMediNexus    13 February 2018

A recent study published in Digestive Endoscopy assessed the feasibility and safety of same-day regimen of low-volume polyethylene glycol solution with ascorbic acid for bowel cleansing before colonoscopy in children. Here, a retrospective analysis was conducted on data on children who received polyethylene glycol solution with ascorbic acid for bowel cleansing. This pilot study entailed the use of polyethylene glycol solution with ascorbic acid in 112 pediatric patients, between July 2013 and November 2014. Among these, 81% patients were able to orally ingest the prescribed amount of polyethylene glycol solution with ascorbic acid. Meanwhile, satisfactory bowel cleansing could be attained in 87% on intention-to-treat analysis and 85% on per-protocol analysis. Cleansing grade was significantly better in children who ingested polyethylene glycol solution with ascorbic acid within 60 minutes. Moreover, there were no serious adverse events. Thus, it was concluded that same-day regimen of polyethylene glycol solution with ascorbic acid is effective and safe for bowel cleansing in children.

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