Studies have discovered links between atopic dermatitis (AD) and diverse comorbidities. The present study appraised evidence of this association among adults.

It discovered evidence regarding 32 statements. The study identified:

• Clear evidence of the relationship between AD in adults and select allergic, atopic, immune-mediated mental health and bone health conditions and skin ailments. 
• Some evidence backs a link between AD and substance use, attention deficit hyperactivity disorder and components of metabolic syndrome. 
• A small association with various cardiovascular conditions. 
• An inconclusive link between AD in adults and autism spectrum disorders, myocardial infarction, stroke and metabolic syndrome.

This analysis relies on the best available evidence; however, it does not make recommendations for screening or managing comorbidities in adults with AD.

Clinicians must be insightful about comorbidities associated with AD. Additional research is needed to establish the effectiveness of screening or managing comorbidities in adults with AD.

Source: Davis DMR, Drucker AM, Alikhan A, et al. American Academy of Dermatology Guidelines: Awareness of comorbidities associated with atopic dermatitis in adults. J Am Acad  Dermatol. 2022;86(6):1335-1336.e18.