According to a study published in eBioMedicine, semaglutide can help reduce alcohol dependence by half. Semaglutide is the first medication to act on the GLP-1 receptor that is available in tablet form.

The findings of the study showed that the drug significantly reduced alcohol consumption and alcohol consumption in conjunction with relapses in the test subjects. Interestingly, semaglutide reduced alcohol intake equally in male and female test subjects. 

Relapses in alcohol consumption is a significant problem for the individual with alcohol dependence, as they tend to drink more than before the withdrawal after relapse.

In the study, the researchers examined the mechanism by which the medication reduced alcohol consumption. They found that the drug reduced alcohol-induced reward in the brain, which reduced alcohol consumption. 

They explained that semaglutide affected the brains reward system in test subjects, especially the nucleus accumbens area of the brain, which is part of the limbic system. 

(Source:https://www.daijiworld.com/news/newsDisplay?newsID=1088981)