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eMediNexus 15 August 2023
A team of researchers from the University of Texas Southwestern Medical Center, Dallas in Texas embarked on a mission to ascertain the occurrence the rate of catheter-associated UTIs in cervical cancer patients after radical hysterectomy.
They also aimed to define other factors that increased the risk for catheter-associated UTIs. For this they examined patients with early-stage cervical cancer who underwent the surgery from 2004 to 2020. Data for the patients was obtained from the Gynecologic Oncology surgical and tumor databases of the institution. Patients who lacked adequate follow-up data or had a urinary tract injury or had been administered chemoradiation prior to the surgery were not included in the study group. Catheter-associated UTI was defined as a urinary infection detected within 48 hours of removal of the catheter with bacteriuria >103 cfu/mL and urinary signs and symptoms.
On multivariate analysis, after adjusting for confounding variables, current smoking history and catheterization for more than 7 days emerged as independent risk factors for catheter-associated UTI with adjusted OR (aOR) of 3.94 and 19.49 respectively.
This study has identified risk factors for catheter-associated UTI in the postoperative period, which are potentially modifiable. Hence, it is important to elicit a history of current smoking and measures to quit smoking must be taken prior to the surgery to avoid the risk of postoperative complications such as catheter-associated UTI. Early removal of the urinary catheter should be encouraged within one week of postoperative period in all women who undergo radical hysterectomy for early-stage cervical cancer.
Source:. Am J Obstet Gynecol. 2023 Jun;228(6):718.e1-718.e7.
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