Vitamin D helps in Calcium Absorption

• Vitamin D plays a crucial role in regulating calcium metabolism by enhancing calcium absorption in the intestines. Maintaining a diet rich in both optimal vitamin D and calcium is paramount for the proper mineralization of bones, ensuring their strength and structural integrity.³

Vitamin D helps in osteoblast maturation

• Studies on human osteoblast cell cultures show that glycoxidation negatively impacts the maturation of osteoblasts. However, the adverse effects of glycoxidation on various bone markers can be mitigated by the addition of vitamin D.³

Vitamin D and calcium supplementation mitigates osteoporosis 

• Vitamin D and calcium supplementation leads to hypercalcemia and, ultimately, its storage in the bone, potentially offering therapeutic benefits for bone metabolic disorders such as osteoporosis.³
• A human trial conducted in older women receiving 1200 mg of calcium along with 800 IU of vitamin D daily over a 12-week period found no change in blood calcium concentrations, indicating that calcium was probably stored in the body.³

The prevention of falls and fractures is a common goal for a considerable number of individuals who utilize both vitamin D and calcium.³ The interplay between these two essential nutrients underscores their combined efficacy in supporting bone health.³

Recognizing the Signs That Your Bones Need Extra Support

• Calcium deficiencies may affect all body parts.⁵
• Hypocalcemia most commonly presents as paresthesia, muscle spasms, cramps, tetany, circumoral numbness, and seizures.⁶
• It can also present with laryngospasm, neuromuscular irritability, cognitive impairment, personality disturbances, prolonged QT intervals, electrocardiographic changes that mimic myocardial infarction, or heart failure.⁶

Absorption Rate of Different Calcium Salts

• To ensure sufficient calcium intake, a variety of calcium supplements are easily accessible.⁷ Among these, calcium carbonate and calcium citrate are the two most prevalent and extensively researched options.⁷
• Recent studies have shown the superior absorbability of Active absorbable algal calcium (AAACa) over other forms.
• Studies highlight distinct advantages of marine-derived calcium over calcium carbonate supplements and other calcium-rich foods, which are difficult to absorb and increase gastric burden.⁸

Superior Intestinal Absorption:

AAA Ca stands out for being the most efficiently absorbed from the intestine compared to other calcium compounds.⁹

Effective Parathyroid Hormone Suppression:

The heightened absorption capability of AAA Ca leads to more effective suppression of parathyroid hormone secretion, thereby mitigating the indirect process through which PTH stimulates calcium release and ultimately prevents excessive bone resorption.⁹

Enhanced Bone Mineral Density:

AAA Ca not only suppresses parathyroid hormone but also contributes to increased bone mineral density.⁹

Reduced Vertebral Fracture Risk:

The efficient absorption of AAA Ca correlates with a decreased risk of vertebral fractures.⁹

Calcium Paradox Phenomenon:

The unique properties of AAA Ca, particularly its outstanding absorbability, play a crucial role in counteracting calcium deficiency and making the calcium paradox phenomenon more recognizable.⁹

Realizing the Calcium Paradox:

Only by successfully countering calcium deficiency with AAA Ca, known for its exceptional absorbability, can we bring the phenomenon of calcium paradox into a recognizable reality within our reach.⁹