Scientists from the University of Bristol and NHSBT have identified a new blood group system, MAL, resolving a 50-year mystery about the AnWj antigen. A new genetic test will improve blood donor matching and patient care globally.

A team of researchers from the University of Bristol and NHS Blood and Transplant (NHSBT) has unveiled a new blood group system called MAL, solving a 50-year-old mystery surrounding the elusive AnWj antigen. This discovery paves the way for improved blood donor identification and enhanced patient care for those with rare blood types.

Under the leadership of senior research scientist Dr. Louise Tilley, the team developed a genetic test to detect patients lacking the AnWj antigen. He noted that while estimating the exact number of beneficiaries is hard, approximately 400 patients annually rely on NHSBT as a last resort.

The International Blood Group Reference Laboratory in Filton has created a test compatible with existing genotyping platforms, facilitating the global sharing of antibodies for research. Nicole Thornton, head of the laboratory, emphasized the significance of this advancement in enhancing patient safety and efficacy in blood transfusions worldwide.

(Source:https://www.business-standard.com/health/scientists-discover-new-blood-group-after-a-50-year-mystery-details-inside-124091801166_1.html )