The goal of a study published in Neuromodulation was to assess whether transcutaneous electrical stimulation (TES) can improve symptoms of defecation and soiling in children with chronic constipation without slow-transit constipation (STC) and transit delay in the anorectum. This study included 10 children with treatment-resistant constipation, of which four were females from 5-10 years of age, presenting to a tertiary hospital with gastrointestinal nuclear transit study (NTS) showing normal proximal colonic transit and anorectal holdup of tracer. It was observed that nine of these children had <3 bowel motions (BM) per week. While after three months of TES, defecation frequency increased in nine out of the 10 participants; six patients out of these nine improved to ≥3 BM per week. Additionally, soiling reduced in nine out of the 10 patients. Furthermore, nine among the patients included either reduced or stopped laxative use. Meanwhile, quality-of-life of these children improved to within the normal range. From the results, it was stated that TES improved symptoms of constipation in over 50% of children with treatment-resistant constipation and isolated holdup in the anorectum.