Antibiotic prophylaxis in children with vesicoureteral reflux increases risk of multidrug resistance
According to a meta-analysis reported online June 28, 2018 in the journal Pediatrics, antibiotic prophylaxis in children with vesicoureteral reflux increases the risk of multidrug resistance among recurrent infections. Children who received antibiotic prophylaxis were more likely to have a multidrug-resistant infection (33% vs 6%) and they were also more likely to receive broad-spectrum antibiotics (68% vs 49%).
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