A Dutch trial of the use of sildenafil in pregnant women has been abruptly stopped after 11 infants born to women who received the medication died according to the Amsterdam University Medical Center (Amsterdam UMC).

The STRIDER (Sildenafil Therapy in Dismal Prognosis Early-Onset Fetal Growth Restriction) trial, which included 11 hospitals across the Netherlands and in other countries, started in 2015 and was to have finished in 2020. It was designed to determine whether sildenafil could increase fetal growth by increasing blood flow to the placenta in women whose fetus was severely underdeveloped. (Medscape)